Influence of oral acyclovir on ocular complications of herpes zoster ophthalmicus

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Anterior segment complications of herpes zoster ophthalmicus.

TOPIC The clinical features and management strategies for varicella-zoster virus (VZV) infections of the cornea, lids, and adnexa. CLINICAL RELEVANCE Herpes zoster ophthalmicus (HZO) can result in a myriad of chronic and recurrent complications that may be sight threatening. Surgical intervention is the mainstay of treatment, and advancements in this area may lessen the complications of HZO i...

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Ocular manifestations in herpes zoster ophthalmicus.

BACKGROUND Ocular complications of herpes zoster ophthalmicus (HZO) may lead to substantial visual disability, severe post-herpetic neuralgia and rarely fatal cerebral complications. AIM To identify the pattern of ocular manifestation in herpes zoster ophthalmicus. MATERIALS AND METHODS A cross-sectional descriptive study was under taken including the clinically diagnosed cases of HZO. All ...

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Topical acyclovir in herpes zoster ocular involvement.

Topical acyclovir has been found in 15 out of 18 patients to control, without recurrences and in an appreciably shorter time than if steroids were used, keratoconjunctivitis induced by herpes zoster. Once steroids were started, recurrences occurred during withdrawal of steroids or after they had been stopped.

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Oral acyclovir in acute herpes zoster.

Oral acyclovir at a dose of 800 mg five times daily for seven days was compared with placebo in a randomised double blind trial conducted at three centres in the United Kingdom. The study group comprised 205 elderly immune competent patients suffering from herpes zoster who were entered within 72 hours of the onset of rash. Acyclovir significantly reduced the times to arrest of new lesion forma...

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Herpes Zoster Ophthalmicus

INTRODUCTION Herpes zoster is a common diagnosis in the emergency department (ED). Caused by the reactivation of the varicellazoster virus (VZV), zoster usually presents as a painful dermatomal rash. In addition to skin or mucosal involvement, VZV reactivation commonly affects the ophthalmic division of the trigeminal nerve and subsequently the eye. This manifestation is termed herpes zoster op...

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ژورنال

عنوان ژورنال: Eye

سال: 1994

ISSN: 0950-222X,1476-5454

DOI: 10.1038/eye.1994.13